# Chemicals of Concern {% tabs %} {% tab title="The basics" %} The presence of toxic chemicals in food packaging associated with harm to humans and the environment is well documented. Hundreds of different harmful substances can be present in the various types of materials used in food packaging, and they can migrate in different amounts and at different rates depending on many factors. Certain chemicals are linked to negative human health effects when consumed through this pathway - these are referred to as **Chemicals of Concern (CoCs)**. You can view the CoCs considered with the UP Scorecard as defined by the [Food Contact Chemicals Priority (FCCprio) List](https://zenodo.org/records/17199870/files/FCCprio-List-v0-2-Zenodo-20260115.xlsx?download=1). Sustainable foodware must be safe for both the environment and humans. With this metric, the UP Scorecard helps to ensure this by considering whether foodware or packaging items contain CoCs, guiding users to avoid the most concerning substances and move towards healthier materials.

Simplified illustration of how chemicals can migrate into food from foodware and food packaging.

{% endtab %} {% tab title="More details" %} ### Food Contact Chemicals and Migration Food contact materials (FCMs) are used to make food contact articles (FCAs) that come into contact with food and beverages during, for example, processing, storing, packaging, or consumption. The chemicals within these FCMs and FCAs are known as **food contact chemicals (FCCs)**.

Thousands of chemicals are used in the manufacture of food packaging articles.

FCCs are found in all food contact materials. Over 15'000 FCCs are known to be intentionally added substances (IAS; such as additives and processing aids). There can also be thousands (up to 100'000 according to some experts) of non-intentionally added substances (NIAS; such as impurities, contaminants, breakdown products, and reaction by-products) present in FCMs. There is scientific evidence that many FCCs can migrate from foodware and packaging into foodstuffs: thousands of FCCs have been detected in migrates and extracts from food contact materials and articles.

Some of the FCCs detected in migrates and extracts from FCMs.

*** ### Chemicals of Concern FCCs can contaminate food when they migrate into the food, resulting in human exposure to complex chemical mixtures. Some FCCs have hazard properties defined as harmful. They are known as Chemicals of Concern (CoCs), and they can affect both the environment and human health in many different ways.

FCCs are present in FCMs, they can migrate into foodstuff, and potentially end up being ingested by humans. Various international biomonitoring programs, databases, and primary literature now provide evidence that hundreds of FCCs have been found in human bodies.

Studies report on FCCs found in human bodies. This is often done by analyzing samples of blood, urine, breast milk, and/or hair for the presence of FCCs.

Considering the scientific evidence, reducing or eliminating CoCs from foodware and packaging is a critical step towards safer and more sustainable products and food systems. The CoC metric within the UP Scorecard is meant to guide decision-makers who want to improve their chemical safety standards for foodware and packaging. {% endtab %} {% tab title="Scoring" %} **Indicator:** scale from 2 - 20 {% hint style="info" %} The Chemicals of Concern (CoC) metric is intended to help suppliers better understand their products' chemical impact and empower purchasers to eliminate chemicals of concern from their portfolios and ask for safer ingredients. {% endhint %} To provide a starting point and pathway to safer foodware and packaging, a matrix approach was developed that considers **(1)** the **presence of chemicals of concern** in the packaging material, and **(2)** the **migration potential** of chemicals in the food being packaged. These scores are then combined to calculate **(3)** an **overall CoC score.** Where only limited or highly uncertain data were available to inform the score, this is visually communicated to the user on the scorecard's results page. More details are available in the [Chemicals of Concern section](https://upscorecard.org/methodology-document-chemicals) of the full methodology document. ### Presence Score To evaluate the human health impact of a foodware or packaging article, the first aspect to address is whether there are any intentionally added and potentially harmful chemicals in a product. The UP Scorecard does this by asking users to check for these chemicals and then to disclose the reliability of this claim. #### **Compliance with the FCCprio List** Providing that the information is available (or can be obtained by talking with manufacturers or suppliers), users can compare the chemicals intentionally used in manufacturing a product with the Food Packaging Forum's [Food Contact Chemicals Priority (FCCprio) List](https://zenodo.org/records/17199870/files/FCCprio-List-v0-2-Zenodo-20260115.xlsx?download=1).

Are there intentionally used chemicals of concern in my product? The FCCprio List has four tiers of priority chemicals of concern to avoid.

Compliance with the FCCprio List's tiers of priority chemicals can help suppliers and purchasers stay ahead of future regulations and consumer concerns. If a product does not intentionally contain any of the 1,200+ chemicals listed in the 4 tiers, it can get the highest score. If at least one chemical from tier 1 is intentionally present, the product gets the worst score. The score can be progressively improved by manually confirming that chemicals from tiers 1, 2, 3, and 4 are not intentionally used in the product. {% embed url="" %} How to access the FCCprio List in the UP Scorecard and assess chemical compliance and declaration. {% endembed %} #### **Applying a Disclosure Level** The scorecard also rewards the disclosure level used to declare compliance with the FCCprio List. Users can declare different levels of disclosure that a product does not intentionally contain any of the chemicals in one or more of the tiers:

If a product is accompanied by a third-party verified disclosure, it can get a higher CoC score. Conversely, a self-declared claim without traceability would get a lower score.

*** ### Migration Potential Score Beyond just containing a chemical of concern, another important aspect is the likelihood of the chemical migrating into the food (and exposing the consumer). This is directly linked to the inertness of the food contact material (**material inertness**) and to the conditions in which the food contact article is used (defining **food and material interactions**). #### Material Inertness The release of chemicals into food depends on the inertness of the material, which describes how possible it is for chemicals to move into and out of the material. Some materials are endowed with extremely high barrier properties (they do not let any chemical through), while other more porous materials have very poor barrier properties. In the UP Scorecard, generic food contact materials were scored by scientific experts from very low to very high migration potential (see Section 4.5 of the [full methodology document](https://upscorecard.org/methodology-document-chemicals) for details). Beyond just describing the migration of intentionally used CoCs, considering the material inertness also helps to take into account the potential migration of many additional chemicals that can be present known as non-intentionally added substances (NIAS). These are often entirely unknown and untested chemicals present in a material as contaminants, degradation products, or reaction by-products from the production process. They too can have hazardous properties and threaten consumer health.

A product with high inertness will get a higher score, and vice-versa.

#### Food and Material Interaction There is scientific evidence showing that the release of chemicals from foodware and packaging into foodstuffs is influenced by various factors characterizing the storage and usage conditions. Such factors include storage time, temperature, fat content, acidity, as well as container size.

Factors that promote increased migration of chemicals from food contact materials into food.

In the UP Scorecard, an example worst-case scenario with the highest food and material interactions (leading to the most chemical migration) would be a hot, oily, acidic soup served in a small cup. A pre-defined set of common foods is available in the scorecard for users to apply. Users can also create and save custom foods to use in their product comparisons by providing some basic information about the food's properties and storage conditions. *** ### Overall Chemicals of Concern Score The overall CoC score combines the Presence Score and the Migration Potential Score as shown in Equation 1. This score is then linearly normalized to be within the range of 1 (worst) to 100 (best) so as to match the scoring range of the other five metrics. $$ (1):Overall\space CoC\space Score = Presence\space Score + Migration\space Potential\space Score $$

*** ### Example Scores The graphic below shows the default CoC score for a highly inert material (ceramic) and a less inert material (PP). The graphic also shows the influence of the foodstuff being packaged on the CoC score. In both cases, the default compliance score is assumed (meaning that CoCs may be intentionally used in both products). A user could manually improve the scores by confirming compliance with the FCCprio List based on a high disclosure level.

How the default chemicals of concern score can change based on packaging and food type.

{% endtab %} {% tab title="Additional links" %}


Methodology: Chemicals of Concern	Methodology document.png	https://upscorecard.org/methodology-document-chemicals
Food Contact Chemicals Priority (FCCprio) List	4.png	https://zenodo.org/records/17199870/files/FCCprio-List-v0-2-Zenodo-20260115.xlsx?download=1
FitNESS open coursware: Universe of food contact chemicals	Fitness Universe of FCCs.png	https://fitness.agroparistech.fr/fitness2/online/FPF/universe-of-food-contact-chemicals.html

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